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Hyperpigmentation with Optilight

 TITLE  A Multi-Mechanism Skin Brightening Regimen Delivers Pigment Evening Benefits in an Ethnically Diverse Population
 AUTHOR  Brenda L. Edison, BA, Barbara A. Green, RPh et al.
PUBLICATION Poster presented at the 21st Congress of the European Academy of Dermatology & Venereology, Prague, Czech Republic, 27 – 30 September 2012
YEAR 2012


A new brightening skincare regimen was developed to improve the complexion of facial skin by targeting multiple steps and pathways that affect pigmentation. The regimen consists of a facial cleanser, serum and lotion, which contain N-acetyl glucosamine* plus a variety of other benefit ingredients to collectively exfoliate pigmented areas, reduce tyrosinase activity and melanin production, and deliver an overall pigment evening effect.


N-acetyl glucosamine is known as NeoGlucosamine® in Exuviance products.


Overall improvement in skin pigmentation

  • 93% of users achieved a more even skin tone after the first 4 weeks.
  • 60% of subjects noticed an improvement as early as 2 weeks.
  • 90% of subjects rated excellent, very good or good improvement after 16 weeks.
  • Users reported more even pigmentation, less obvious brown spots, and improved clarity and radiance at the end of the 16 weeks visit.

User self-assessment on improvement during the 3 visits

Photography evidence of improvement with the use of the regimen

Visual grading and clinical photos showed

  • Lighter and more even skin colour
  • Brighter overall skin tone
  • Reduced overall sallowness
  • Lighter and less apparent brown spots
  • Effects were observed in all ethnic groups

Self-assessment questionnaires confirmed that subjects noticed brighter skin tone, more even pigmentation, and less apparent brown spots

Marked improvement in pigmentation in standard lighting photographs and in cross-polarized photographs with melanin imaging applied to visualize hyperpigmented areas.